Safety and efficacy of antimicrobial peptides against naturally acquired leishmaniasis.

نویسندگان

  • J Alberola
  • A Rodríguez
  • O Francino
  • X Roura
  • L Rivas
  • D Andreu
چکیده

Leishmaniases, which are important causes of morbidity and mortality in humans and dogs, are extremely difficult to treat. Antimicrobial peptides are rarely used as alternative treatments for naturally acquired parasitic diseases. Here we report that the acylated synthetic antimicrobial peptide Oct-CA(1-7)M(2-9) is safe and effective for treating naturally acquired canine leishmaniasis.

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عنوان ژورنال:
  • Antimicrobial agents and chemotherapy

دوره 48 2  شماره 

صفحات  -

تاریخ انتشار 2004